Medicago is pursuing an aggressive discovery and development program that encompasses pandemic and trivalent vaccines, antivirals, antibodies and biologics – including biosimilars and biobetters.
Rotavirus is the most common cause of severe diarrhea among infants and young children; nearly every child in the world will have been infected with rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe, and adults are rarely affected.
- Although there are several species of rotavirus, type A Rotavirus causes more than 90% of rotavirus infections in humans. Rotavirus infects cells in the small intestine and causes gastroenteritis ("stomach flu").
- It is a particularly important cause of morbidity and mortality in the developing world. More than 450,000 children under age 5 die from rotavirus infection each year, mostly in developing countries, and almost two million more become severely ill.
- Public health campaigns to combat rotavirus focus on providing oral rehydration therapy for infected children and vaccination to prevent the disease.